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Our findings that mitAspAT catalyzes a cysteine S -conjugate β-lyase reaction with TFEC in vitro and is syncatalytically inactivated in the process (Cooper et al., 2002a) are consistent with the in vivo finding that this enzyme in the kidney is thioacylated after administration of TFEC to rats (Cooper et al., 2011)

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Histopathological analysis reveals that SAC attenuates mucosal damage and inflammatory infiltration (Fig