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Glucose-6-phosphate dehydrogenase (G6PD) deficiency: Video | Osmosis

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Because conjugation of the electrophilic AFB 1 -8,9-epoxide with GSH is an alternative fate to binding to nucleophilic centers in cellular macromolecules, GSTs play a critical role in the protection of tissues from the deleterious effects of bioactivated AFB 1 , and tissues vary considerably in both GST concentration and distribution of specific GST isoforms