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However, it remained possible that normal levels of TrxR2 protein, though perhaps lower than normal levels of TrxR1 protein (see above), might be sufficient to compensate for loss of TrxR1 without an associated increase in mRNA levels

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For instance, if a patient dies from sepsis associated with multidrug-resistant bacteria, the cause may be reported as sepsis more often than the involvement of the bacteria 20,27