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The Endocrine Society position on testosterone therapy emphasizes the importance of comprehensive approaches to men’s hormonal health, which often includes considering growth factors like IGF-1

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As a non-specific yet highly effective intervention strategy, exercise can directly enhance immune cell activity and reshape immune subset distribution at the cellular level [13] while simultaneously delaying the aging process at the systemic level by improving overall metabolic status, modulating the neuroendocrine–immune network [14], and activating anti-inflammatory mechanisms [15]

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