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Our previous studies, using in vitro cell culture as well as in vivo animal models have also demonstrated that enzymes cytochrome c oxidase (Complex IV) and aconitase are extremely sensitive to mitochondrial-ROS induced oxidative stress in comparison to other complexes [23],[38],[42],[43]

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Glutathione is a powerful antioxidant produced by the body, composed of three amino acids: glutamine, cysteine, and glycine