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In the presence of secondary somatic mutations, the P72R SNP has been shown to exert differential effects on tumorigenesis that is dependent on SNP identity [25]

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[DOI] [PMC free article] [PubMed] [Google Scholar] Nicklin P, Bergman P, Zhang B, Triantafellow E, Wang H, Nyfeler B, Yang H, Hild M, Kung C, Wilson C, Myer VE, MacKeigan JP, Porter JA, Wang YK, Cantley LC, Finan PM, Murphy LO