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Studies in vitro [70] and in vivo [71] demonstrate that NAC can suppress expression of several important neuroinflammatory molecules including matrix metalloproteinases, TNF-alpha, interleukin 1beta and inducible nitric oxide synthase in lipopolysaccharide-stimulated microglial cells and in a rat model of experimental stroke

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"Lipoprotein lipase in the arterial wall: linking LDL to the arterial extracellular matrix and much more"