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Although we expected the largest microbiome differences to occur in the lean control group relative to the obese control group, we found that the diet-switched groups exhibited a greater number of differences from the control groups than the control groups did from one another

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In humans, cyanocobalamin must undergo intracellular enzymatic conversion to the active coenzyme forms—methylcobalamin and adenosylcobalamin—which, depending on the pH environment, can interconvert with hydroxocobalamin (Obeid et al., 2015)