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4.2.1 8-hydroxy-2′-deoxyguanosine (8-OHdG) 8-Hydroxy-2′-deoxyguanosine (8-OHdG) is widely recognized as the most frequently detected and studied marker of oxidative DNA damage, resulting from the attack of reactive oxygen species, specifically hydroxyl radicals on the C8 position of guanine residues

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