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One study, for instance, notes that people who are overweight or obese appear to have lower levels of vitamin B12 than those with a body mass index (BMI) that falls within the range considered to be “normal.” People who took vitamin B12 supplements of their own volition gained between 2.5 and 17 fewer pounds (1.2–7.7 kg) over ten years compared to those who did not take any form of supplementation with this vitamin

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That single block sets off a chain of changes inside fat cells