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Structurally, this places tesamorelin in a separate class from both AOD-9604 a growth hormone fragment and GLP-1 S, a GLP-1 receptor agonist, since tesamorelin’s activity depends on stimulating endogenous hormone release rather than mimicking a fragment or incretin hormone directly

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Verdict at a Glance CagriSema and retatrutide represent two fundamentally different approaches to next-generation obesity treatment