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The risk of alcoholic liver disease by inducing proinflammatory cytokine production and apoptosis is also increased [8]

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The mechanism appears to involve: TBI-induced BBB disruption facilitating spirochete CNS access Shared inflammatory pathways amplifying neuroinflammation Mitochondrial dysfunction from both conditions creating severe energy deficit Overlapping autonomic dysregulation Beyond Lyme: The Coinfection Complexity The Polymicrobial Reality Ticks are vectors for multiple pathogens simultaneously