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Under physiological condition, ATF7 acts as an epigenetic repressor by recruiting histone H3K9 dimethyltransferase G9a to the promoters of activation-related genes (such as Cxcl2, Ccl3, Stat1, Myo10, Nfkb2 and Tap1), thereby maintaining macrophage at the resting state

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Human HGF, at a concentration of 0.08 ng/ μ l with or without drugs, was incubated with heparin at a final concentration of 5 μ g/ml