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Starting with lower doses and increasing gradually prevents any initial stimulating effects from feeling excessive

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The published briefing memos for prior PCAC peptide reviews have read as conservative on clinical-need findings: if there is a plausible FDA-approved alternative for the named indication — mesalamine for ulcerative colitis, for instance — the agency tends to find that the bulks-list path is unnecessary, regardless of whether the alternative is what compounding patients actually want