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Systemic safety: The underexamined question Before summarizing the evidence, it is worth pausing on a category that receives almost no attention in the cosmeceutical and biohacking literature: the systemic safety profile of peptides with only topical evidence

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Preclinical (animal) data Rodent studies suggest BPC-157 may: Promote blood vessel growth Enhance tendon fibroblast activity Reduce inflammation Protect gastrointestinal tissues However, these findings: Use doses far above any human equivalent Use controlled laboratory injuries Do not predict human efficacy 2