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Among these are the 5′-adenosine monophosphate-activated protein kinase (AMPK), mitogen-activated protein kinase (MAPK), and the Janus kinase signal transducer and activator of transcription JAK-STAT) pathways, which aid in the control of cellular proliferation, mitosis, apoptosis and most aspects of the immune response [24,25,26,27,28,29,30,31,32]
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Glutamine becomes conditionally essential in hyper-catabolic states In healthy animals the body is able to synthesize considerable quantities of glutamine and there is no apparent evidence of a shortage