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Research has focused on Melanotan 1’s role in melanocortin receptor pharmacology, pigmentation biology, and cutaneous photoprotection mechanisms — with its high MC1R selectivity distinguishing it from non-selective melanocortin agonists and making it a valuable research comparator alongside PT-141, which targets the CNS-expressed MC3R and MC4R subtypes

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This is primarily to reduce the likelihood of gastrointestinal discomfort rather than to enhance absorption, and is consistent with the administration advice in the levocarnitine Summary of Product Characteristics (SmPC)